All the 21 octogenarians operated after January 2006 survived surgery, with excellent 5 year survival (85.1 ± 7.9%). Five year survival was markedly improved in patients operated after January 2006 compared to those operated in the early years of the experience (92.3 ± 2.3% vs. Overall, 5 and 10 year survival rates were 85 ± 2.5% and 57.2 ± 5.7%, respectively. In-hospital mortality was 4.1% (n=11) but differed significantly between the first 100 patients operated before 2006 and the last 168 patients operated after January 2006 (8 vs. Mean overall follow-up was 4.9 ± 3.1 years and was complete in all patients. 12.1 ± 5.4 mmHg, P < 0.0001 respectively) in 3 months of follow-up. Peak and mean trans-aortic gradient decreased significantly (75.0 ± 29.1 vs. Mean age, Charlson comorbidity index and Euro-score were 71.0 ± 9.2 years, 4.2 ± 1.5 and 10.2 ± 11 respectively, and 156 (58%) were male. Methods and Results: Between 19, 268 patients underwent primary aortic valve replacement with a Freestyle bioprosthesis, 211 (79%) of them in the sub-coronary position. Objectives: To report the outcomes of patients after aortic valve replacement with the Freestyle® stentless bioprosthesis in the Tel Aviv Medical Center followed for ≤ 15 years. < 10% of sleeping time spent with SpO 2 < 90%) ( P = 0.03).Ĭonclusions: Severe nocturnal hypoxemia in non-diabetic patients with moderate to severe sleep apnea might affect glucose regulation primarily during REM sleep.īackground: Stentless aortic bioprostheses were designed to provide improved hemodynamic performance and potentially better survival. Mean SpO 2 and percentage of time spent at SpO 2 30% vs.
Methods: Seven non-diabetic patients with moderate to severe sleep apnea were connected to a continuous glucose-monitoring sensor while undergoing overnight polysomnography. Objectives: To investigate the effect of hypoxemia and nocturnal glucose homeosatsis in non-diabetic patients with sleep apnea. However, the effect of hypoxic episodes on nocturnal glucose regulation in non-diabetic patients is unknown. Background: Obstructive sleep apnea has been shown to be associated with impaired glucose metabolism and overt diabetes mellitus.
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